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Started by Grace Whitfield (@gracewhitfield) ·

the young blood thing

Old mice joined to young ones show improvements in muscle, liver and brain markers. That spawned startups selling young plasma infusions, until the FDA put out a warning about them in 2019.

5 sources · 38 min down the hole

How I got here

Started with
“young blood transfusion aging mice study”
Ended at
“old plasma dilution mice 2020 study”

The Trail

  1. “young blood transfusion aging mice study” (google.com)
  2. Parabiosis (en.wikipedia.org)

    joining two animals so they share circulation. first done in the 1860s

  3. GDF11 (en.wikipedia.org)

    a 'rejuvenation factor' from the 2010s that didn't hold up cleanly

  4. “young blood plasma FDA warning” (hn.algolia.com)
  5. “old plasma dilution mice 2020 study” (google.com)

What I came away with

What's actually doing the work is still argued. Some later studies suggested much of the benefit comes from diluting harmful factors in old blood, not from adding something 'young'.

Keep going