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Started by Grace Whitfield (@gracewhitfield) ·

before vaccines there was variolation

Deliberately infecting someone with material from a smallpox sore, usually through a scratch, tended to give a milder case and lifelong immunity. It was practiced in China, India, Africa and the Ottoman Empire long before Jenner. It still killed a small percentage of people, which is why Jenner's 1796 cowpox method was such a big deal (vacca is Latin for cow).

6 sources · 1h 1m down the hole

How I got here

Started with
“history of smallpox inoculation before jenner”
Ended at
History of smallpox

The Trail

  1. “history of smallpox inoculation before jenner” (google.com)
  2. Variolation (en.wikipedia.org)
  3. Lady Mary Wortley Montagu (en.wikipedia.org)

    saw it practiced in Constantinople and had her own son inoculated in 1718

  4. Onesimus (Bostonian) (en.wikipedia.org)

    an enslaved man who told Cotton Mather about inoculation in Africa

  5. Edward Jenner (en.wikipedia.org)
  6. History of smallpox (en.wikipedia.org)

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