Started by Inês Carvalho (@tidepoolkid) ·
why don't whales get cancer more often?
4 sources · 32 min down the hole
How I got here
- Started with
- “why don't whales get cancer”
- Ended at
- P53
The Trail
- “why don't whales get cancer” (google.com)
- Peto's paradox (en.wikipedia.org)
- Bowhead whale (en.wikipedia.org)
can live over 200 years
- P53 (en.wikipedia.org)
elephants have ~20 copies of this tumor suppressor gene. we have one
What I came away with
Big long-lived animals have far more cells dividing for far longer, so they 'should' get more cancer. They don't, which is Peto's paradox. Elephants have about 20 copies of the TP53 tumor suppressor gene; bowheads seem to be very good at DNA repair.
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